Modelreduction

We provide here the code that was used to model order reduce the networks in the paper 'A systematic, algorithmic methodology for model reduction of large-scale biochemical networks' by Yo-Cheng Chang and Antonis Papachristodoulou.

The Yeast Glycolysis Pathway

One zip file containing:

The SIMULINK model: YGlyco_mdl.mdl The S-function: YGlyco_sfun.mdl The Parameters: YGlyco_para.m The vector field: YGlyco_eqs.m The ODE function: YGlycoode.m

The reduction algorithm: YGlyco_reduction.m The system coordinate change function: findtransform.m The norm coordinate change function: getQ.m

The EGFR-MAPK Pathway

One zip file containing:

The SIMULINK model: EGFRMAPK_mdl.mdl The S-function: EGFRMAPK_sfun.mdl The Parameters: EGFRMAPK_para.m The total concentrations: EGFRMAPK_init.m The ODE function: EGFRMAPKode.m

The reduction algorithm: EGFR_reduction.m The system coordinate change function: findtransform.m The norm coordinate change function: getQ.m