Difference between revisions of "SynBioControl2017"

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A Workshop on Control Engineering and Synthetic Biology will be held and 12th of September 2014 at [http://www.worc.ox.ac.uk Worcester College], University of Oxford. This was funded by the Engineering and Physical Sciences Research Council ([http://www.epsrc.ac.uk EPSRC]), under projects [http://sysos.eng.ox.ac.uk/control/sysos/index.php/Control_Engineering_Inspired_Design_Tools_for_Synthetic_Biology EP/I031944/1, EP/I032223/1 and EP/I03210X/1].
+
__NOTOC__
 +
<center>
 +
== International Workshop==
 +
==on Control Engineering and Synthetic Biology ==
 +
<h4> What next? </h4>
 +
</center>
 +
 
 +
----
  
 
<center>
 
<center>
[[Image:workshop1.jpg|700px]]
+
[[File:GroupPhoto.jpg|900px]]
 
</center>
 
</center>
 +
 +
An '''International Workshop on Control Engineering and Synthetic Biology''' will be held on the 17th and 18th July 2017 at the [http://www.princephiliphouse.com/ '''Royal Academy of Engineering - Prince Philip House'''], 3 Carlton House Terrace, SW1Y 5DG, London. This event is '''supported by the Engineering and Physical Sciences Research Council''' ([http://www.epsrc.ac.uk EPSRC]), under projects  [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/M002187/1 EP/M002187/1] and [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/M002454/1 EP/M002454/1].
 +
 +
'''Organisers:''' Guy-Bart Stan (Imperial College London),  Antonis Papachristodoulou (University of Oxford), Filippo Menolascina (University of Edinburgh).
 +
 +
<center>
 +
[[File:synbiocontrol2017Header.gif]] &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;  [[Image:sponsor-hires.jpg|300px]]
 +
</center>
 +
----
 +
 +
== Delegate leaflet ==
 +
The delegate leaflet containing our welcoming message, programme of talks, poster abstracts, and travel information can be [http://sysos.eng.ox.ac.uk/wiki/images/2/2e/Delegate_Leaflet.pdf downloaded here].
 +
 +
==Twitter==
 +
If you use Twitter, please label your tweets with the hashtag '''#synbiocontrol2017''' for easy searching and sorting.
  
 
== Description ==
 
== Description ==
  
Designing and implementing effective methods of control in a living cell
+
 
has the potential to dramatically change biotechnology.
+
Designing and implementing effective feedback control in living cells has the potential to dramatically change biotechnology. However, before this potential is realised, a number of theoretical and practical challenges must be addressed, which lie at the interface between control engineering and synthetic biology. This workshop will discuss both the challenges and the opportunities that Synthetic Biology offers. A specific focus will be on the “next grand challenges” the field of synthetic biology and how control engineering can address them. An exceptional group of speakers, world leaders in synthetic biology and control engineering, will present recent progress, identify challenges and share their vision of where synthetic biology is headed and how the control engineering community can contribute to delivering its promise.
However, before this potential is realised, a number of both theoretical
+
 
and practical challenges must be met. The workshop on control
+
*'''''Control Engineering Themes''''':
and synthetic biology covered both the challenges and the
+
Modelling, analysis, and design of reliable synthetic circuits as well as regulation of synthetic processes.
opportunities involved with this area. Both synthetic biology and
+
 
control engineering topics were discussed.
+
*'''''Synthetic Biology Themes''''':
*''<B>Control Engineering Themes:</B>''
+
Challenges and opportunities for implementing designs and enabling effective synthetic regulation and control.
Modelling, analysis, and design of reliable synthetic circuits as well
+
 
as regulation of synthetic processes.
+
----
*''<B>Synthetic Biology Themes:</B>''
+
 
Challenges and opportunities for implementing designs and enabling
+
== Registration ==
effective synthetic regulation and control.
+
 
 +
Registration is now closed - contact us if you have any queries.
  
 
== Confirmed Speakers ==
 
== Confirmed Speakers ==
  
*[http://www.mit.edu/~ddv/ Professor Domitilla del Vecchio], MIT.
+
*[http://www.imperial.ac.uk/people/f.ceroni Francesca Ceroni], Imperial College London
  
*[http://www.cds.caltech.edu/~murray Professor Richard Murray], Caltech. [[Media:Murray.pdf|Slides]]
+
*[http://yvchen.bol.ucla.edu/ Professor Yvonne Chen], UCLA
  
*[http://www.csb.ethz.ch/people/joergs Professor Joerg Stelling], ETHZ. [[Media:Stelling.pdf|Slides]]
+
*[https://team.inria.fr/ibis/hidde-de-jong/ Professor Hidde de Jong], INRIA
  
*[http://www.bsse.ethz.ch/ctsb/people/people_PI/khammash Professor Mustafa Khammash], ETHZ.
+
*[https://sites.google.com/site/dibernardogroup/ Professor Mario di Bernardo], University of Bristol and University of Naples. [http://sysos.eng.ox.ac.uk/wiki/images/f/f7/Synbio_multicellular_control_dibernardo.pdf Slides]
  
*[http://biodynamics.ucsd.edu/profiles/jeff Professor Jeff Hasty], UCSD.
+
*[http://elsamadlab.ucsf.edu/ Professor Hana El Samad], UCSF
  
*[http://sbie.kaist.ac.kr/sub_0101.php Professor Kwang-Hyun Cho], KAIST
+
*[http://www.cambridgeconsultants.com/ Dr. Richard Hammond], Cambridge Consultants. [http://sysos.eng.ox.ac.uk/wiki/images/a/ae/P1789-P-153_v0.3.pdf Slides]
  
*[http://swainlab.bio.ed.ac.uk/ Professor Peter Swain], University of Edinburgh.
+
*[http://biodynamics.ucsd.edu/profiles/jeff Professor Jeff Hasty], UCSD
  
*[http://groups.csail.mit.edu/synbio/ Professor Ron Weiss], MIT.
+
*[https://uwaterloo.ca/centre-for-theoretical-neuroscience/people-profiles/brian-ingalls Professor Brian Ingalls], University of Waterloo.[http://sysos.eng.ox.ac.uk/wiki/images/b/b0/2017_Ingalls.pdf Slides]
  
*[http://www.ncl.ac.uk/computing/people/profile/natalio.krasnogor Professor Natalio Krasnogor], University of Newcastle. [[Media:Krasnogor.pdf|Slides]]
+
*[http://www.bsse.ethz.ch/ctsb/people/people_PI/khammash Professor Mustafa Khammash], ETHZ
  
*[http://www3.eng.cam.ac.uk/~rs771/ Professor Rodolphe Sepulchre], University of Cambridge. [[Media:Sepulchre.pdf|Slides]]
+
*[http://www.cds.caltech.edu/~murray Professor Richard Murray], Caltech. [http://sysos.eng.ox.ac.uk/wiki/images/7/78/Murray-recombinases_london-18Jul17.pdf Slides]
  
*[http://www2.warwick.ac.uk/fac/sci/eng/staff/dgb/ Professor Declan Bates], University of Warwick.
+
*[https://www.microsoft.com/en-us/research/people/aphillip/ Dr Andrew Phillips], Microsoft Research [http://sysos.eng.ox.ac.uk/wiki/images/3/3b/APhillips_SynBioControl2017.pdf Slides]
  
*Dr Lionel Clarke, UK Synthetic Biology Leadership Council.
+
*[http://www.synpromics.com/about-us/our-team/michael-l-roberts-phd Michael Roberts], Synpromics
  
*[http://www2.warwick.ac.uk/fac/sci/lifesci/people/ajaramillo/ Professor Alfonso Jaramillo], University of Warwick.
+
*[http://researcher.watson.ibm.com/researcher/view.php?person=ie-GRusso Dr. Giovanni Russo], IBM Research
  
*[http://research.microsoft.com/en-us/people/ndalchau/ Dr Neil Dalchau], Microsoft Research. [[Media:Dalchau.pdf|Slides]]
+
*[https://www.researchgate.net/profile/Velia_Siciliano Dr. Velia Siciliano], Imperial College London. [https://drive.google.com/file/d/0B2H3R1gWZYg0aGlEQ2dNMlRKelk/view?usp=sharing Slide]
  
*Dr Jordan Ang, Imperial College London.
+
*[http://swainlab.bio.ed.ac.uk/ Professor Peter Swain], University of Edinburgh. [https://elifesciences.org/articles/21415 Paper]
  
*[http://www-control.eng.cam.ac.uk/Main/PG364 Mr Peyman Gifani], University of Cambridge.
+
----
  
*[http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Edward Dr Edward Hancock], University of Oxford.
+
== Workshop schedule ==
 +
{| class="wikitable"
 +
!
 +
! 17 July
 +
! colspan="3" | 18 July
 +
|-
 +
| 8.30 AM
 +
| style="text-align: center;" | Coffee
 +
| rowspan="2" colspan="3"  style="text-align: center;"|  Coffee
 +
|-
 +
| 8.50 AM
 +
| style="text-align: center;" | Introduction
 +
|-
 +
| 9 AM - 9:45 AM
 +
| style="text-align: center;" | '''Mustafa Khammash'''
 +
<br>
 +
''Theory and methods for biomolecular control systems''
 +
| colspan="3" style="text-align: center;" |
 +
'''Richard Murray'''<br>
 +
<br>
 +
''Recombinase-based circuits''<br>
 +
''for environmental detection diagnostics, and logging''
 +
|-
 +
| 9:45 AM - 10:30 AM
 +
|  colspan="3" style="text-align: center;" |
 +
'''Mario di Bernardo'''<br>
 +
<br>
 +
''Design, implementation and in-silico analysis ''<br>
 +
''of multi-cellular feedback control strategies'' <br>
 +
''in synthetic bacterial consortia''
 +
| colspan="3" style="text-align: center;" | ''' Hana El Samad '''<br>
 +
<br>
 +
''Real-time optogenetic compensation strategies''<br>
 +
''to operationally investigate feedback regulation''
 +
|-
 +
| 10:30 AM - 11 AM
 +
|  style="text-align: center;" |  Coffee Break
 +
| colspan="3"  style="text-align: center;" |  Coffee Break
 +
|-
 +
| 11 AM -11:45 AM
 +
|  style="text-align: center;" |  '''Michael Roberts''' <br>
 +
<br>
 +
''Precision in gene regulation using synthetic promoters''
 +
| colspan="3" style="text-align: center;" |  '''Velia Siciliano''' <br>
 +
<br>
 +
''The second wave of mammalian synthetic biology:''<br>
 +
''engineering safer synthetic devices''<br>
 +
|-
 +
| 11:45 AM - 12:30 PM
 +
| style="text-align: center;" |  '''Richard Hammond''' <br>
 +
<br>
 +
''Finding needles in haystacks: a high-throughput ''<br>
 +
''platform for genetic constructs screening''
 +
| colspan="3"  style="text-align: center;" |  '''Yvonne Chen''' <br>
 +
<br>
 +
''Engineering next-generation T cells''<br>
 +
''for cancer immunotherapy''
 +
|-
 +
| 12:30 PM - 2 PM
 +
|  style="text-align: center;" |  Lunch / Poster session
 +
| colspan="3"  style="text-align: center;" |  Lunch / Poster session
 +
|-
 +
| 2 PM - 2:45 PM
 +
| style="text-align: center;" |  '''Peter Swain''' <br>
 +
<br>
 +
''Distributing tasks via multiple input pathways''<br>
 +
''increases survival in stress''
 +
| colspan="3"  style="text-align: center;" |  '''Andrew Phillips''' <br>
 +
<br>
 +
''Programming languages for molecular and genetic devices''<br>
 +
|-
 +
| 2:45 PM - 3:30 PM
 +
| style="text-align: center;" |  '''Hidde de Jong''' <br>
 +
<br>
 +
''Natural and synthetic control''<br>
 +
'' of resource allocation in bacteria''
 +
| colspan="3" style="text-align: center;" |  '''Giovanni Russo''' <br>
 +
<br>
 +
''How to synchronize and de-synchronize biochemical circuits''
 +
|-
 +
| 3:30 PM - 4:15 PM
 +
| style="text-align: center;" |  Coffee break / Poster session
 +
| colspan="3"  style="text-align: center;" |  Coffee break / Poster session
 +
|-
 +
|4:15 PM - 5 PM
 +
| style="text-align: center;" |  '''Brian Ingalls''' <br>
 +
<br>
 +
''Synthetic biology approaches to suppression of antibiotic resistance:''<br>
 +
''toward model-based design''<br>
  
== Timetable ==
+
| colspan="3" style="text-align: center;" |  '''Francesca Ceroni''' <br>
 +
<br>
 +
''Characterisation of host-construct interactions''<br>
 +
''for synthetic biology''<br>
 +
|-
 +
|  5 PM - 5:45 PM
 +
| style="text-align: center;" |  Poster session (5-6 PM)
 +
| colspan="3" style="text-align: center;" |  '''Jeff Hasty''' <br>
 +
<br>
 +
''Engineered gene circuits: from clocks to synchronized delivery''<br>
 +
|-
 +
| 6 PM - 7 PM
 +
|  style="text-align: center;" |  Networking / Free time
 +
| colspan="3" style="text-align: center;" |  Final remarks<br>
 +
<br>
 +
''Where do we go from here?''
 +
|-
 +
|7 PM-10 PM
 +
| style="text-align: center;" |  Dinner for the speakers
 +
| colspan="3" |
 +
|}
  
The timetable is [[Media:Workshop_forwebsite.pdf|available to download]].
+
== Location of the Workshop ==
  
== Location of the Workshop ==
+
Prince Philip House at 3 Carlton House Terrace is an historic Grade I listed building, overlooking The Mall and St James’s Park and a short walk from Trafalgar Square. The corresponding postcode is SW1Y 5DG.
 +
 
 +
==Accommodation for Attendees ==
 +
 
 +
As an attendee, you can locate and book accommodation directly via this [https://www.speedybooker.com/group/default.aspx?g=imperial&brand=imperial&partnerid=50&lang=en link].
 +
 
 +
An array of hotel/accommodation venues are available upon search. Most venues fall within reach of a local underground station from which you can board the Piccadilly Line to reach the venue. Alternatively travel by taxi is feasible.
 +
Note: Bookings and availabilities are dealt with on a '''first-come first-served''' basis. It is recommended to book your accommodation in as advance as possible.
 +
 
 +
For enquiries solely and specifically on bookings/availabilities only, you can contact:
  
Worcester College is located within walking distance from Oxford's city centre. The workshop took place in the Linbury Lecture theatre and the poster sessions were held in the Morley Fletcher Room. Please see the [[Media:Worcester_College_Map.pdf|College Map]] for more information.  
+
Email: vacenquiries@imperial.ac.uk
  
== Travel Information ==
+
Telephone: +44 (0)20 7594 9507
  
Directions to Oxford can be found [http://www.oxford.gov.uk/PageRender/decTS/How_to_get_to_Oxford_occw.htm here]. It is within easy reach of [http://www.bhx.co.uk Birmingham Airport], [http://www.heathrowairport.com Heathrow Airport], [http://www.gatwickairport.com Gatwick Airport] and [http://www.southamptonairport.com Southampton International Airport]. Information on the best way to travel to Oxford can be found [http://www.eng.ox.ac.uk/contact-us/travel-to-the-department here]. Car Parking within Oxford is extremely limited and expensive. If you are coming by car it is recommended that you use the Pear Tree or Water Eaton [http://www.oxford.gov.uk/PageRender/decTS/Park_and_Ride_occw.htm Park and Ride facilities].
+
If you have any further queries, please contact Nazib Ahmed: n.ahmed@imperial.ac.uk
  
Worcester College has also provided us with [[Media:Travel_info.pdf|directions]].
+
== Travel Information ==
  
== Flyer and Registration Form ==
+
The venue is close to several bus and tube stops and there are plenty of hotels nearby or a few stops away. Please see our [http://sysos.eng.ox.ac.uk/wiki/images/2/2e/Delegate_Leaflet.pdf delegate leaflet] for travel information and nearest tube stations.
  
* [[Media:synbioworkshop_registration.doc|Registration form (in .doc format)]]
+
== Posters ==
* [[Media:synbioworkshop_registration.pdf|Registration form (in .pdf format)]]
 
  
<center>
+
Everyone participating in the workshop is invited to bring a poster to display their work.
[[Image:sponsor-hires.jpg|300px]]
 
</center>
 

Latest revision as of 11:07, 21 August 2019

International Workshop

on Control Engineering and Synthetic Biology

What next?


GroupPhoto.jpg

An International Workshop on Control Engineering and Synthetic Biology will be held on the 17th and 18th July 2017 at the Royal Academy of Engineering - Prince Philip House, 3 Carlton House Terrace, SW1Y 5DG, London. This event is supported by the Engineering and Physical Sciences Research Council (EPSRC), under projects EP/M002187/1 and EP/M002454/1.

Organisers: Guy-Bart Stan (Imperial College London), Antonis Papachristodoulou (University of Oxford), Filippo Menolascina (University of Edinburgh).

Synbiocontrol2017Header.gif                                         Sponsor-hires.jpg


Delegate leaflet

The delegate leaflet containing our welcoming message, programme of talks, poster abstracts, and travel information can be downloaded here.

Twitter

If you use Twitter, please label your tweets with the hashtag #synbiocontrol2017 for easy searching and sorting.

Description

Designing and implementing effective feedback control in living cells has the potential to dramatically change biotechnology. However, before this potential is realised, a number of theoretical and practical challenges must be addressed, which lie at the interface between control engineering and synthetic biology. This workshop will discuss both the challenges and the opportunities that Synthetic Biology offers. A specific focus will be on the “next grand challenges” the field of synthetic biology and how control engineering can address them. An exceptional group of speakers, world leaders in synthetic biology and control engineering, will present recent progress, identify challenges and share their vision of where synthetic biology is headed and how the control engineering community can contribute to delivering its promise.

  • Control Engineering Themes:

Modelling, analysis, and design of reliable synthetic circuits as well as regulation of synthetic processes.

  • Synthetic Biology Themes:

Challenges and opportunities for implementing designs and enabling effective synthetic regulation and control.


Registration

Registration is now closed - contact us if you have any queries.

Confirmed Speakers


Workshop schedule

17 July 18 July
8.30 AM Coffee Coffee
8.50 AM Introduction
9 AM - 9:45 AM Mustafa Khammash


Theory and methods for biomolecular control systems

Richard Murray

Recombinase-based circuits
for environmental detection diagnostics, and logging

9:45 AM - 10:30 AM

Mario di Bernardo

Design, implementation and in-silico analysis
of multi-cellular feedback control strategies
in synthetic bacterial consortia

Hana El Samad


Real-time optogenetic compensation strategies
to operationally investigate feedback regulation

10:30 AM - 11 AM Coffee Break Coffee Break
11 AM -11:45 AM Michael Roberts


Precision in gene regulation using synthetic promoters

Velia Siciliano


The second wave of mammalian synthetic biology:
engineering safer synthetic devices

11:45 AM - 12:30 PM Richard Hammond


Finding needles in haystacks: a high-throughput
platform for genetic constructs screening

Yvonne Chen


Engineering next-generation T cells
for cancer immunotherapy

12:30 PM - 2 PM Lunch / Poster session Lunch / Poster session
2 PM - 2:45 PM Peter Swain


Distributing tasks via multiple input pathways
increases survival in stress

Andrew Phillips


Programming languages for molecular and genetic devices

2:45 PM - 3:30 PM Hidde de Jong


Natural and synthetic control
of resource allocation in bacteria

Giovanni Russo


How to synchronize and de-synchronize biochemical circuits

3:30 PM - 4:15 PM Coffee break / Poster session Coffee break / Poster session
4:15 PM - 5 PM Brian Ingalls


Synthetic biology approaches to suppression of antibiotic resistance:
toward model-based design

Francesca Ceroni


Characterisation of host-construct interactions
for synthetic biology

5 PM - 5:45 PM Poster session (5-6 PM) Jeff Hasty


Engineered gene circuits: from clocks to synchronized delivery

6 PM - 7 PM Networking / Free time Final remarks


Where do we go from here?

7 PM-10 PM Dinner for the speakers

Location of the Workshop

Prince Philip House at 3 Carlton House Terrace is an historic Grade I listed building, overlooking The Mall and St James’s Park and a short walk from Trafalgar Square. The corresponding postcode is SW1Y 5DG.

Accommodation for Attendees

As an attendee, you can locate and book accommodation directly via this link.

An array of hotel/accommodation venues are available upon search. Most venues fall within reach of a local underground station from which you can board the Piccadilly Line to reach the venue. Alternatively travel by taxi is feasible. Note: Bookings and availabilities are dealt with on a first-come first-served basis. It is recommended to book your accommodation in as advance as possible.

For enquiries solely and specifically on bookings/availabilities only, you can contact:

Email: vacenquiries@imperial.ac.uk

Telephone: +44 (0)20 7594 9507

If you have any further queries, please contact Nazib Ahmed: n.ahmed@imperial.ac.uk

Travel Information

The venue is close to several bus and tube stops and there are plenty of hotels nearby or a few stops away. Please see our delegate leaflet for travel information and nearest tube stations.

Posters

Everyone participating in the workshop is invited to bring a poster to display their work.