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'''Dr Thomas P. Prescott'''
 
 
 
Post-Doctoral Research Associate
 
 
 
[[Main_Page|SySOS Control Group]], Department of Engineering Science, University of Oxford
 
 
 
thomas.prescotteng.ox.ac.uk
 
 
 
= Background =
 
I am currently a Post-Doctoral Research Associate in Control Engineering with [[User:Antonis|Professor Antonis Papachristodoulou]], in the SySOS group at the Department of Engineering Science in the University of Oxford. As a student of Trinity College, University of Oxford, I received an MMath in Mathematics in 2008, and in 2015 I completed my DPhil (i.e. PhD) in Engineering Science as part of the Life Sciences Interface Doctoral Training Centre, funded by an EPSRC scholarship. My thesis, supervised by Antonis Papachristodoulou, focused on decomposition and reduction techniques for large-scale ODE models, with applications to models used in Systems and Synthetic Biology. Between these two degrees, I also spent two years as an Operational Research consultant in industry.
 
 
 
= Interests =
 
* Layered architecture of complex systems
 
* Mathematical and Systems Biology
 
* Synthetic Biology
 
* Networked, multi-scale models of dynamical systems
 
* Structured model reduction and error propagation
 
 
 
Additionally, past projects have been in:
 
* Community detection in networks of time series (with [http://people.maths.ox.ac.uk/porterm/ Mason Porter] and [https://www.linkedin.com/in/ealeicht Elizabeth Leicht])
 
* Decentralized congestion control in the Internet
 
 
 
My work as an OR consultant at Tui centred on:
 
* Yield/revenue management (specifically, using price-sensitive optimization)
 
* Search algorithms
 
 
 
= Publications =
 
== Journal Papers ==
 
# T. P. Prescott & A. Papachristodoulou. ''Designing conservation relations in layered synthetic biomolecular networks.'' IEEE Transactions on Biomedical Circuits and Systems (Synthetic Biology Special Edition), 2015 (in press)
 
# T. P. Prescott, [http://www.csb.ethz.ch/group/members/person-detail.html?persid=161944 M. Lang], & A. Papachristodoulou. ''Quantification of interactions between dynamic cellular network functionalities by cascaded layering.'' PLoS Computational Biology, 11(5):e1004235, 2015 [http://dx.doi.org/10.1371/journal.pcbi.1004235 DOI] [[Prescott2015_PLOS|PDF]]
 
# T. P. Prescott & A. Papachristodoulou. ''Layered decomposition for the model order reduction of timescale separated biochemical reaction networks.'' Journal of Theoretical Biology, 356:113-122, 2014 [http://dx.doi.org/10.1016/j.jtbi.2014.04.007 DOI] [[Media:Prescott2014_JTB.pdf|PDF]]
 
# T. P. Prescott & A. Papachristodoulou. ''Guaranteed error bounds for structured complexity reduction of biochemical networks.'' Journal of Theoretical Biology, 304:172-182, 2012 [http://dx.doi.org/10.1016/j.jtbi.2012.04.002 DOI] [[Media:Prescott2012.pdf|PDF]]
 
 
 
== Peer Reviewed Conference Proceedings ==
 
# T. P. Prescott & [http://www.mit.edu/~gyorgy/ A. Gyorgy]. ''Bounding the effect of retroactivity in the presence of parameter uncertainty.'' Proceedings of the American Control Conference (ACC), Chicago IL, pp.3120-3125, July 2015 [http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7171812 IEEExplore] [[Media:Prescott2015_ACC|PDF]]
 
# T. P. Prescott & A. Papachristodoulou. ''Structured storage functions for cascaded systems.'' Proceedings of the IEEE Conference on Decision and Control (CDC), Los Angeles CA, pp.5488-5493, December 2014 [http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=7040247 IEEExplore] [[Media:Prescott2014_CDC.pdf|PDF]]
 
# T. P. Prescott & A. Papachristodoulou. ''Synthetic Biology: A Control Engineering Perspective.'' Proceedings of the European Control Conference (ECC), Strasbourg, France, pp.1182-1186, June 2014 [http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6862638 IEEExplore] [[Media:PreP14_ECC14.pdf|PDF]]
 
# T. P. Prescott & A. Papachristodoulou. ''Signal propagation across layered biochemical networks.'' Proceedings of the American Control Conference (ACC), Portland OR, pp.3399-3404, June 2014 [http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6858808 IEEExplore] [[Media:Prescott2014_ACC.pdf|PDF]]
 
# T. P. Prescott & A. Papachristodoulou. ''Layering in networks: The case of biochemical systems.'' Proceedings of the American Control Conference (ACC), Washington D.C., pp.4544-4549, June 2013 [http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6580539 IEEExplore] [[Media:Prescott2013.pdf|PDF]]
 
 
 
= Code =
 
Any code associated with published research can be found [[/Code|here]].
 
 
 
= Teaching =
 
Teaching in Michaelmas (MT) and Hilary (HT) [http://www.ox.ac.uk/about_the_university/university_year/dates_of_term.html terms] at University of Oxford.
 
* Class tutor, Engineering Science intercollegiate classes
 
** C10.3 Biosystem Modelling (HT2015)
 
* Demonstrator, [http://www.sbcdt.ox.ac.uk/ Synthetic Biology CDT]
 
** Synthetic Circuit Design (HT2015)
 
** Systems & Control Theory for Synthetic Biology (HT2015)
 
** Introduction to Systems and Synthetic Biology (MT2014)
 
* Class tutor, Maths Institute intercollegiate classes
 
** C6.2b Networks (HT2014)
 
* Teaching Assistant, Maths Institute intercollegiate classes
 
** B5a Techniques of Applied Mathematics (MT2013)
 
** B5b Applied PDEs (HT2013)
 
** B8a Mathematical Biology (MT2012)
 
* Class tutor, Biochemistry/Biomedical Sciences
 
** Mathematics for Biomedical Sciences Prelims (MT2012 - HT2014)
 

Latest revision as of 15:43, 14 March 2020