Difference between revisions of "Welcome to SYSOS"

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       <h2 class="brand-name text-center hidden-sm hidden-xs"><span class="label label-default">Welcome to SySOS</span></h2>
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      <h2 class="text-center"> Welcome to SySOS</span></h2>
 
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        <h5 class="text-center" style="margin-bottom:20px;">A group researching complex networked control systems, biological and technological</h5>
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      <h4 class="subheader" class="text-center" style="margin-bottom:20px;">A group researching complex networked control systems, biological and technological</h4>
 
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<!--<center> <span style="color:#F00000; font-size:200%;"> [http://sysos.eng.ox.ac.uk/wiki/index.php/SynBioControl2019 '''Synthetic Biology and Control Workshop'''] </span></center> -->
 
<!--
 
<!--
<center> <span style="color:#F00000; font-size:200%;"> [https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=123718 '''NEW! Control Engineering/Synthetic Biology Postdoc position available'''] </span></center> -->  
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<center> <span style="color:#F00000; font-size:200%;"> [https://eng.ox.ac.uk/study/research-studentships/research-studentship-in-control-engineering/ '''NEW! Funded DPhil (PhD) position available!'''] </span></center> -->
 
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Our group develops tools and algorithms for the analysis and design of biological and technological systems and applies them in a range of areas, from Synthetic Biology to fluid mechanics. In particular, we have been developing theory to understand how '''nonlinear networked systems (System of Systems)''' operate how to design control laws for them, using computational tools based on the '''Sum of Squares decomposition and Semidefinite Programming'''. We have been applying this theory to understand and (re)design biological systems (Systems and Synthetic Biology) but also to analyse and design control laws for fluid flows, robust synchronization, multi-agent system consensus, smart power networks and congestion control for the Internet. Here is a short summary of the areas we work on - please follow the links below for more details.
+
== Research Interests ==
  
* Nonlinear systems analysis, Sum of Squares optimization and Lyapunov techniques. In this spirit, we have developed methods for stability analysis of systems described by Ordinary, Delay and Partial Differential Equations, as well as switched/hybrid systems.
+
Our group develops tools and algorithms for the analysis and design of feedback control in biological and technological systems and applies them in a range of areas, from Synthetic Biology to fluid mechanics. In particular, we have been developing theory to understand how '''nonlinear networked systems (System of Systems)''' operate how to design control laws for them, using computational tools based on the '''Sum of Squares (SOS) decomposition and Semidefinite Programming (SDP)'''. We have been applying this theory to understand and (re)design biological systems (Systems and Synthetic Biology) but also to analyse and design control laws for fluid flows, robust synchronization, multi-agent system consensus, smart power networks, the robustness of (deep) neural network controllers and congestion control for the Internet. Here is a short summary of the areas we work on - please follow the links below for more details.
  
* Systems and Synthetic Biology. We collaborate closely with groups in Engineering Science (Professor Wei Huang) Oxford Biochemistry (Dr George Wadhams and Professor Judith Armitage) and other institutions for understanding biological pathways through mathematical modelling using experimental data and designing new experiments for model invalidation (Systems Biology), as well as proposing and implementing redesigns for existing biological systems for improved performance (Synthetic Biology).  
+
* Nonlinear systems analysis, Sum of Squares optimization and Lyapunov techniques. In this spirit, we have developed methods for stability analysis of systems described by Ordinary, Delay and Partial Differential Equations, as well as switched/hybrid systems. Of current interest is how to scale these tools to handle much more complicated and richer system descriptions, of higher dimension (see also point below, on scaling SDP/SOS methods).
 +
 
 +
* Systems and Synthetic Biology. We collaborate closely with groups in Engineering Science (Professor Wei Huang) and Plant Sciences (Professor Philip Poole) and other institutions for understanding biological pathways through mathematical modelling using experimental data and designing new experiments for model invalidation (Systems Biology), as well as proposing and implementing redesigns for existing biological systems for improved performance (Synthetic Biology).  
  
 
* Software Development (SOSTOOLS). This can be found [http://www.eng.ox.ac.uk/control/sostools here].
 
* Software Development (SOSTOOLS). This can be found [http://www.eng.ox.ac.uk/control/sostools here].
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* Fluid mechanics and Heat transfer, from a control perspective. We are taking a control engineering approach to understand questions in Hydrodynamic Stability and mechanisms for background noise energy amplification and subsequent reduction. We are also using a Sum of Squares approach for the stability analysis and control design of systems described by Partial Differential Equations.
 
* Fluid mechanics and Heat transfer, from a control perspective. We are taking a control engineering approach to understand questions in Hydrodynamic Stability and mechanisms for background noise energy amplification and subsequent reduction. We are also using a Sum of Squares approach for the stability analysis and control design of systems described by Partial Differential Equations.
  
*Complexity reduction of networked systems. We are investigating methods based on model decomposition and reduction to facilitate computational analysis and identification of large-scale and nonlinear systems. Systems of interest include biochemical reaction networks, power systems and consensus networks.
+
* Complexity reduction of networked systems. We are investigating methods based on model decomposition and reduction to facilitate computational analysis and identification of large-scale and nonlinear systems. Systems of interest include biochemical reaction networks, power systems and consensus networks.
 +
 
 +
* Scaling Sum of Squares and Semidefinite Programming. We are using sparsity- and symmetry-exploiting algorithms for improving the scalability of semidefinite programming, including the development of software (such as [https://github.com/oxfordcontrol/CDCS CDCS]) to implement relevant operator-splitting algorithms.
 +
 
 +
* Robust analysis and design of (deep) neural network controllers. We are using tools from traditional and modern control theory for the analysis and design of (deep) neural network controllers used in (deep) reinforcement learning.
  
 
== Current Members ==
 
== Current Members ==
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* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Antonis Professor Antonis Papachristodoulou] - Academic
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Antonis Professor Antonis Papachristodoulou] - Academic
  
* [https://michaelschaub.github.io/ Dr Michael Schaub] - Marie Skłodowska Curie Fellow, July 2017-
+
* [https://www.plants.ox.ac.uk/people/patrick-green Mr Patrick Green] - DPhil candidate, July 2019-. Co-supervised with Professor Philip Poole.
 +
 
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Matt Mr Matthew Newton] - DPhil Candidate, October 2019 -.
 +
 
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Manos Mr Emmanouil Alexis] - DPhil Candidate, October 2019 -. Co-supervised with Professor Luca Cardelli.
 +
 
 +
* [https://www.miroslavgasparek.com Mr Miroslav Gasparek] - DPhil Candidate, October 2019 -. Co-supervised with Professor Harrison Steel.
 +
 
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Han Mr Han Wang] - DPhil Candidate, October 2020 -. Co-supervised with Professor Kostas Margellos.
 +
 
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Scott Mr Scott Stacey] - Probationary Research Student, July 2021  -. Co-supervised with Professor Harrison Steel.
 +
 
 +
* [https://rhizosphere.org/people/bergthor-traustason/ Mr Bergthor Traustason] - Probationary Research Student, July 2021 -. Co-supervised with Professor Philip Poole.
  
* [https://sites.google.com/site/aivarsootla/ Dr Aivar Sootla] - Post-Doctoral Research Associate, September 2016-
+
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Liqun Mr Liqun Zhao] - Probationary Research Student, October 2021 -. Co-supervised with Dr Konstantinos Gatsis.
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:JSB Mr James Scott-Brown] ( [http://sysos.eng.ox.ac.uk/tebio/ project page], [http://www.jamesscottbrown.com personal site])- DPhil Candidate, October 2014-. Co-supervised with Dr Jonathan David (dstl).
+
== Current and Previous Externally Funded Projects ==
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Yang Mr Yang Zheng] - DPhil Candidate, October 2015-
+
* [http://www.synbio-cdt.ac.uk EPSRC & BBSRC Centre for Doctoral Training in Synthetic Biology] [http://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/L016494/1]
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Harry Mr Harrison Steel] - DPhil Candidate, October 2016-
+
* [http://sysos.eng.ox.ac.uk/wiki/index.php/Designing_feedback_control_in_Synthetic_Biology EPSRC Fellowship for Growth in Synthetic Biology: Designing Feedback Control in Biology for Robustness and Scalability] [http://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/M002454/1]
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Licio Mr Licio Romao] - DPhil Candidate, October 2017-. Co-supervised with Professor Kostas Margellos.
+
* [https://www.imperial.ac.uk/aeronautics/fluiddynamics/sumofsquares/index.php Sum-of-Squares Approach to Global Stability and Control of Fluid Flows] [http://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/J010537/1]
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Carolin Ms Carolin Schulte] - Probationary Research Student, July 2018-. Co-supervised with Professor Philip Poole.
+
* [http://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/J012041/1 Autonomous Behaviour and Learning in an Uncertain World] [http://www.robots.ox.ac.uk/~parg/aisp/doku.php]
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Boon Mr Boon Lim] - Probationary Research Student, October 2018-. Co-supervised with Professor Wei Huang.
+
*[http://sysos.eng.ox.ac.uk/control/sysos/index.php/Control_Engineering_Inspired_Design_Tools_for_Synthetic_Biology Control Engineering Inspired Design Tools for Synthetic Biology] [http://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/I031944/1]
  
== Current Externally Funded Projects ==
+
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/Designing_Sustainable_Policies_for_Greenhouse_Gas_Emissions Using Control Theory to Design Sustainable Policies for Greenhouse Gas Emissions in the Presence of Model Uncertainty] [http://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/H03062X/1]
  
* [http://sysos.eng.ox.ac.uk/wiki/index.php/Designing_feedback_control_in_Synthetic_Biology EPSRC Fellowship for Growth in Synthetic Biology: Designing Feedback Control in Biology for Robustness and Scalability] [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/M002454/1]
+
* [http://sysos.eng.ox.ac.uk/control/RoSBNet RoSBNet: Network in Synthetic Biology.]  
  
* [http://www.synbio-cdt.ac.uk EPSRC & BBSRC Centre for Doctoral Training in Synthetic Biology] [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/L016494/1]
+
* European Space Agency project with GMV (Spain), NGC (Canada) and the University of Leicester, "Worst-Case and Safety Analysis Tools for Autonomous Rendezvous Systems".
 +
 
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/Chemotaxis_in_Rhodobacter_sphaeroides:_A_Feasibility_Study Control Theory Tools for Elucidating the Phosphotransfer Network in ''Rhodobacter sphaeroides'': A Feasibility Study]  
 +
<!--* [http://www.eng.ox.ac.uk/control/sysos/index.php/Project_page Project page <i>Restricted Access</i>]-->
 +
 
 +
* Oxford-Princeton Collaboration on Network Science with [http://www.princeton.edu/~chiangm/ Professor Mung Chiang.]
  
 
== Collaborations ==
 
== Collaborations ==
  
*[http://control.asu.edu/ Analysis of Functional Differential Equations Using Sum of Squares Programming - ASU, U.S.A.]
+
* [https://coe.northeastern.edu/people/sznaier-mario/ Scaling Semidefinite Programming - Northeastern, USA]
*[https://engineering.jhu.edu/gayme/ A Control Engineering Approach for Modelling High-Shear Flows - Johns Hopkins] [http://www.mckeon.caltech.edu/]
+
* [https://www.l2s.centralesupelec.fr/en/u/valmorbida-giorgio/ Analysis of Partial Differential Equations Using Sum of Squares Programming - CentraleSupelec, France]
*[http://www.ist.uni-stuttgart.de/forschung/themen/networks/index.en.html Multi-Agent-Systems and Delay Robustness in Cooperative Control - IST, Stuttgart]
+
* [https://me.jhu.edu/faculty/dennice-gayme/ A Control Engineering Approach for Modelling High-Shear Flows - Johns Hopkins]  
 +
* [https://www.northumbria.ac.uk/about-us/our-staff/k/ciaran-kelly/ Designing bio-feedback control circuits using small RNA - Northumbria]
  
 
==News==
 
==News==
* [http://sysos.eng.ox.ac.uk/wiki/index.php/User:Antonis Antonis Papachristodoulou] is elevated to IEEE Fellow for his contributions to analysis and design of networked control systems.  
+
* [https://sites.google.com/view/emerging-topics-system-control/home Stockholm Workshop on Emerging Topics in Systems and Control], KTH Royal Institute of Technology, Stockholm, Sweden, June 15-16, 2022.
 +
* [https://sites.google.com/view/ieee-css-societal-challenges22/home?authuser=0 2022 IEEE CSS Workshop on Control for Societal-Scale Challenges] - June 17-18, 2022 Stockholm, Sweden.
 +
* Huge congratulations to [http://sysos.eng.ox.ac.uk/wiki/index.php/User:Licio Dr Licio Romao] for winning the 2021 IET Control and Automation Doctoral Prize  for his thesis [https://ora.ox.ac.uk/objects/uuid:17c1e4dc-42fe-4771-a1a6-bda802dea968 "Scalable and data-driven approaches to convex programming"]! Licio will be giving a [https://events.theiet.org/events/scalable-and-data-driven-approaches-to-convex-programming/ Webinar] on his results - register now!
 +
* Many congratulations to [http://sysos.eng.ox.ac.uk/wiki/index.php/User:Yang Dr Yang Zheng] (see also [https://zhengy09.github.io/ updated website]) who won the 2019 European PhD Award on Control for Complex and Heterogeneous Systems for his thesis [https://ora.ox.ac.uk/objects/uuid:dbf77067-15a0-446a-a909-f9d262e39821 "Chordal Sparsity in Control and Optimization of Large-scale Systems"]!
 +
<center>
 +
[[Image:EECI_zheng.png|x300px]]
 +
</center>
 +
*[http://cmsa.fas.harvard.edu/dynamics-and-randomness Workshop on Dynamics, Randomness, and Control in Molecular and Cellular Networks] Center for Mathematical Sciences and Applications, Harvard University, 12-14 November 2019.
 +
*[http://sysos.eng.ox.ac.uk/wiki/index.php/SynBioControl2019 International Workshop on Control Engineering and Synthetic Biology], Worcester College, Oxford, 9-11 September 2019.
 +
* [https://chi.bio Chi.bio] is released!
 +
<center>
 +
[[Image:chibiofull.jpg|x300px]]
 +
</center>
 +
* Workshop on `New Vistas in computational systems and synthetic biology', May 2019, Vigo, Spain.
 +
* [http://sysos.eng.ox.ac.uk/wiki/index.php/User:Antonis Antonis Papachristodoulou] is elevated to IEEE Fellow for his fundamental contributions to theory and applications of Sum of Squares Programming and networked control systems.
 +
<center>
 +
[[Image:IMG_6863.JPG|x300px]]
 +
</center>
 
* [https://control.ee.ethz.ch/news-and-events/vic.html Workshop on Vistas in Control at ETHZ], September 10-11, 2018.  
 
* [https://control.ee.ethz.ch/news-and-events/vic.html Workshop on Vistas in Control at ETHZ], September 10-11, 2018.  
 
*[https://mbi.osu.edu/event/?id=1063 MBI Workshop on Control of Cellular and Molecular Systems], Mathematical Biosciences Institute, 2-6 October 2017.
 
*[https://mbi.osu.edu/event/?id=1063 MBI Workshop on Control of Cellular and Molecular Systems], Mathematical Biosciences Institute, 2-6 October 2017.
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== Joining SySOS ==
 
== Joining SySOS ==
  
* If you find what we do interesting, and you want to apply for a DPhil (PhD) or MSc by Research in our group, then please [mailto:antonis@eng.ox.ac.uk contact us] sooner than later to discuss possible projects. Note that there are several [http://www.cdt.ox.ac.uk Centres of Doctoral Training] that are relevant to our research, especially the [http://www.synbio-cdt.ac.uk EPSRC & BBSRC CDT in Synthetic Biology] as well as the [http://www.eng.ox.ac.uk/aims EPSRC CDT in Autonomous Intelligent Machines and Systems]. If you have a strong academic background, the chances of securing funding for your studies are higher the earlier you apply. Note that applications need to follow the [http://www.eng.ox.ac.uk/admissions/postgraduate Postgraduate Admissions] guidelines.
+
* If you are an Oxford undergraduate interested in doing a summer internship on any of the above research directions (or anything else) [mailto:antonis@eng.ox.ac.uk get in touch].
 +
 
 +
* If you are finishing your undergraduate/masters degree and you want to apply for a DPhil (PhD) or MSc by Research in our group, then please [mailto:antonis@eng.ox.ac.uk contact us] sooner than later to discuss possible projects. Note that there are several [http://www.cdt.ox.ac.uk Centres of Doctoral Training] that are relevant to our research, especially the [https://www.biodtp.ox.ac.uk/ Interdisciplinary Bioscience DTP] as well as the [http://www.eng.ox.ac.uk/aims EPSRC CDT in Autonomous Intelligent Machines and Systems]. If you have a strong academic background, the chances of securing funding for your studies are higher the earlier you apply. Note that applications need to follow the [http://www.eng.ox.ac.uk/admissions/postgraduate Postgraduate Admissions] guidelines.
  
 
* Any PDRA openings will be advertised on the [http://www.eng.ox.ac.uk/about-us/jobs departmental website]. None are available now.  
 
* Any PDRA openings will be advertised on the [http://www.eng.ox.ac.uk/about-us/jobs departmental website]. None are available now.  
  
* There are several other routes for joining SySOS, mainly through fellowships.
+
* There are several other routes for joining SySOS, mainly through fellowships. Please [mailto:antonis@eng.ox.ac.uk contact us] to discuss.
  
 
== Previous Members ==
 
== Previous Members ==
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Carolin Ms Carolin Schulte] - DPhil student, July 2018- November 2021. Co-supervised with Professor Philip Poole.
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Boon Mr Boon Lim] - DPhil student, October 2018- November 2021. Co-supervised with Professor Wei Huang.
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Licio Mr Licio Romao] - DPhil student, October 2017 - September 2021. Co-supervised with Professor Kostas Margellos.
 +
 +
* [https://www.plants.ox.ac.uk/people/hayley-knights Ms Hayley Knights] - Research Associate, Apr - Sep 2021
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Harry Dr Harrison Steel] - DPhil student, October 2016-June 2019. PDRA, June 2019- September 2020.
 +
 +
* [https://michaelschaub.github.io/ Dr Michael Schaub] - Marie Skłodowska Curie Fellow, July 2017 - June 2020
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Rob Dr Robert Habgood] - PDRA, October 2019 - July 2020
 +
 +
* [https://sites.google.com/site/aivarsootla/ Dr Aivar Sootla] - Post-Doctoral Research Associate, September 2016-June 2019.
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:JSB Mr James Scott-Brown] ([http://sysos.eng.ox.ac.uk/tebio/ project page], [http://www.jamesscottbrown.com personal site])- DPhil Candidate, October 2014-October 2018. Co-supervised with Dr Jonathan David (dstl).
 +
 +
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Yang Mr Yang Zheng] - DPhil Student, October 2015 - March 2019
  
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Nick Dr Nicolas Delalez] - Post-Doctoral Research Associate, January 2016 - January 2019.
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Nick Dr Nicolas Delalez] - Post-Doctoral Research Associate, January 2016 - January 2019.
  
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Axel Dr Axel Nystr&ouml;m] - DPhil Candidate, October 2013-2018. Co-supervised with Dr Andrew Angel.
+
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Axel Dr Axel Nystr&ouml;m] - DPhil Student, October 2013-2018. Co-supervised with Dr Andrew Angel.
  
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Ciaran Dr Ciar&aacute;n Kelly] - Post-Doctoral Research Associate, December 2017-April 2018
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:Ciaran Dr Ciar&aacute;n Kelly] - Post-Doctoral Research Associate, December 2017-April 2018
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* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:August Dr Elias August], October 2007 - December 2008
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/User:August Dr Elias August], October 2007 - December 2008
 
== Completed Projects ==
 
 
* [https://www.imperial.ac.uk/aeronautics/fluiddynamics/sumofsquares/index.php Sum-of-Squares Approach to Global Stability and Control of Fluid Flows] [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/J010537/1]
 
 
* [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/J012041/1 Autonomous Behaviour and Learning in an Uncertain World] [http://www.robots.ox.ac.uk/~parg/aisp/doku.php]
 
 
*[http://sysos.eng.ox.ac.uk/control/sysos/index.php/Control_Engineering_Inspired_Design_Tools_for_Synthetic_Biology Control Engineering Inspired Design Tools for Synthetic Biology] [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/I031944/1]
 
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/Designing_Sustainable_Policies_for_Greenhouse_Gas_Emissions Using Control Theory to Design Sustainable Policies for Greenhouse Gas Emissions in the Presence of Model Uncertainty] [http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/H03062X/1]
 
 
* [http://sysos.eng.ox.ac.uk/control/RoSBNet RoSBNet: Network in Synthetic Biology.]
 
 
* European Space Agency project with GMV (Spain), NGC (Canada) and the University of Leicester, "Worst-Case and Safety Analysis Tools for Autonomous Rendezvous Systems".
 
 
* [http://sysos.eng.ox.ac.uk/control/sysos/index.php/Chemotaxis_in_Rhodobacter_sphaeroides:_A_Feasibility_Study Control Theory Tools for Elucidating the Phosphotransfer Network in ''Rhodobacter sphaeroides'': A Feasibility Study]
 
<!--* [http://www.eng.ox.ac.uk/control/sysos/index.php/Project_page Project page <i>Restricted Access</i>]-->
 
 
* Oxford-Princeton Collaboration on Network Science with [http://www.princeton.edu/~chiangm/ Professor Mung Chiang.]
 
  
 
== Useful Links ==
 
== Useful Links ==
  
 
* [http://www.eng.ox.ac.uk/control Engineering Science Control Group]
 
* [http://www.eng.ox.ac.uk/control Engineering Science Control Group]
 
* [http://www.sysbio.ox.ac.uk/ Oxford Centre for Integrative Systems Biology]
 
  
 
* [http://www.dtc.ox.ac.uk/ Doctoral Training Centres]
 
* [http://www.dtc.ox.ac.uk/ Doctoral Training Centres]

Latest revision as of 06:48, 16 June 2022


Welcome to SySOS


A group researching complex networked control systems, biological and technological



Group 2019.jpg

Research Interests

Our group develops tools and algorithms for the analysis and design of feedback control in biological and technological systems and applies them in a range of areas, from Synthetic Biology to fluid mechanics. In particular, we have been developing theory to understand how nonlinear networked systems (System of Systems) operate how to design control laws for them, using computational tools based on the Sum of Squares (SOS) decomposition and Semidefinite Programming (SDP). We have been applying this theory to understand and (re)design biological systems (Systems and Synthetic Biology) but also to analyse and design control laws for fluid flows, robust synchronization, multi-agent system consensus, smart power networks, the robustness of (deep) neural network controllers and congestion control for the Internet. Here is a short summary of the areas we work on - please follow the links below for more details.

  • Nonlinear systems analysis, Sum of Squares optimization and Lyapunov techniques. In this spirit, we have developed methods for stability analysis of systems described by Ordinary, Delay and Partial Differential Equations, as well as switched/hybrid systems. Of current interest is how to scale these tools to handle much more complicated and richer system descriptions, of higher dimension (see also point below, on scaling SDP/SOS methods).
  • Systems and Synthetic Biology. We collaborate closely with groups in Engineering Science (Professor Wei Huang) and Plant Sciences (Professor Philip Poole) and other institutions for understanding biological pathways through mathematical modelling using experimental data and designing new experiments for model invalidation (Systems Biology), as well as proposing and implementing redesigns for existing biological systems for improved performance (Synthetic Biology).
  • Software Development (SOSTOOLS). This can be found here.
  • Large-scale Networked Systems analysis with communication and structural constraints. Examples in this field come from synchronization phenomena in oscillator networks, Network Congestion Control for the Internet and Power System analysis/Smart grid. We are also looking at multi-agent systems consensus under communication and structural constraints such as the effect of time delays and switching topologies.
  • Fluid mechanics and Heat transfer, from a control perspective. We are taking a control engineering approach to understand questions in Hydrodynamic Stability and mechanisms for background noise energy amplification and subsequent reduction. We are also using a Sum of Squares approach for the stability analysis and control design of systems described by Partial Differential Equations.
  • Complexity reduction of networked systems. We are investigating methods based on model decomposition and reduction to facilitate computational analysis and identification of large-scale and nonlinear systems. Systems of interest include biochemical reaction networks, power systems and consensus networks.
  • Scaling Sum of Squares and Semidefinite Programming. We are using sparsity- and symmetry-exploiting algorithms for improving the scalability of semidefinite programming, including the development of software (such as CDCS) to implement relevant operator-splitting algorithms.
  • Robust analysis and design of (deep) neural network controllers. We are using tools from traditional and modern control theory for the analysis and design of (deep) neural network controllers used in (deep) reinforcement learning.

Current Members

  • Mr Patrick Green - DPhil candidate, July 2019-. Co-supervised with Professor Philip Poole.
  • Mr Emmanouil Alexis - DPhil Candidate, October 2019 -. Co-supervised with Professor Luca Cardelli.
  • Mr Miroslav Gasparek - DPhil Candidate, October 2019 -. Co-supervised with Professor Harrison Steel.
  • Mr Han Wang - DPhil Candidate, October 2020 -. Co-supervised with Professor Kostas Margellos.
  • Mr Scott Stacey - Probationary Research Student, July 2021 -. Co-supervised with Professor Harrison Steel.
  • Mr Bergthor Traustason - Probationary Research Student, July 2021 -. Co-supervised with Professor Philip Poole.
  • Mr Liqun Zhao - Probationary Research Student, October 2021 -. Co-supervised with Dr Konstantinos Gatsis.

Current and Previous Externally Funded Projects

  • European Space Agency project with GMV (Spain), NGC (Canada) and the University of Leicester, "Worst-Case and Safety Analysis Tools for Autonomous Rendezvous Systems".

Collaborations

News

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  • Workshop on `New Vistas in computational systems and synthetic biology', May 2019, Vigo, Spain.
  • Antonis Papachristodoulou is elevated to IEEE Fellow for his fundamental contributions to theory and applications of Sum of Squares Programming and networked control systems.

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Joining SySOS

  • If you are an Oxford undergraduate interested in doing a summer internship on any of the above research directions (or anything else) get in touch.
  • There are several other routes for joining SySOS, mainly through fellowships. Please contact us to discuss.

Previous Members

  • Ms Carolin Schulte - DPhil student, July 2018- November 2021. Co-supervised with Professor Philip Poole.
  • Mr Boon Lim - DPhil student, October 2018- November 2021. Co-supervised with Professor Wei Huang.
  • Mr Licio Romao - DPhil student, October 2017 - September 2021. Co-supervised with Professor Kostas Margellos.
  • Dr Harrison Steel - DPhil student, October 2016-June 2019. PDRA, June 2019- September 2020.
  • Dr Aivar Sootla - Post-Doctoral Research Associate, September 2016-June 2019.
  • Dr Axel Nyström - DPhil Student, October 2013-2018. Co-supervised with Dr Andrew Angel.
  • Dr Thomas Folliard - DPhil student, 2013-2017. Co-supervised with Professor Judith Armitage.
  • Dr Dhruva Raman - DPhil student, 2013-2017. Co-supervised with Dr James Anderson
  • Dr James Anderson DPhil student, 2008 - 2011, Post-Doctoral Research Associate 2011-2012, Junior Research Fellow, 2012-2016.
  • Dr Bing Chu - Postdoctoral Research Assistant, June 2010-March 2012
  • Dr Yo-Cheng (Mark) Chang DPhil, co-supervised with Professor Judith Armitage, Department of Biochemistry, January 2007-January 2011.
  • Dr Bence Mélykúti, DPhil, co-supervised with Professor Alison Etheridge, Department of Statistics, January 2008-February 2011.
  • Miss Nassia Inglessis, September 2009 - October 2009
  • Mr Christoph Maier, April 2009 - July 2009

Useful Links